The collection consists of interviews with Georgia O'Keeffe's surviving relatives, colleagues, friends, and employees as well as supporting project documentation. The bulk of the materials date from 2000 to 2003 and include audiocassette recordings, typed transcripts, photographs, and research and project records.

Margaret Wood (b. 1953) was a companion of O'Keeffe from 1977 to 1982. She is the author of A Painter's Kitchen: Recipes from the Kitchen of Georgia O'Keeffe. Wood was interviewed by Sarah Burt.