The collection consists of interviews with Georgia O'Keeffe's surviving relatives, colleagues, friends, and employees as well as supporting project documentation. The bulk of the materials date from 2000 to 2003 and include audiocassette recordings, typed transcripts, photographs, and research and project records.

Saundra B. Lane is an art collector and widow of William H. Lane (1914-1995). The Lane Foundation owned many modernist paintings and photographs, which it donated to the Museum of Fine Arts, Boston. Lane was interviewed by Jane Cook.